Dual Use Research of Concern (DURC)

 

Responsibilities of the Principal Investigator

Prior to commencing with any activity involving agents of concern, Investigators must:

  • Contact the Department of Environmental Health and Safety (EH&S) to obtain the necessary approvals for access to Biological Select Agents and Toxins (BSAT).
  • Ensure that all personnel, working on the research activity (including him/herself) involving the agents of concern undergoes training in DURC. The ‘DURC Training Certification Form’ is to be used to confirm such training, and is available in the forms and template;library of IRBNet
    • Training is required and involves substantive review and PI-led discussion of the following:
      • FAQs on the US Government for Institutional Oversight of Life Sciences Dual Use Research of Concern, and
      • Training on the U.S. Government Policy for Institutional Oversight of Life Sciences Dual Use Research of Concern
  • Submit to the IRE a completed Dual Use Research of Concern (DURC) Application, available in the forms and template library of IRBNet.
  • Await outcome of review from the IRE regarding applicability of the research as it pertains to this policy (outlined in section II below).
    • If the IRE determines that the research constitutes DURC, and is subject to this Policy: Do not commence with the research until an approved risk mitigation plan is in place.
  • Once an approved risk mitigation plan is in place, and the IRE approves the research to commence, the investigator must conduct and/or communicate the research in accordance with the provisions of the risk mitigation plan
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